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Functional Genomics Studies

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Select item 2002408321.

Maternal oxytocin treatment at birth increases epigenetic age in male offspring [RNA-seq]

(Submitter supplied) Rates of oxytocin use to induce or augment labor are increasing in the United States with little understanding of the impact on offspring development. Using a prairie vole animal model, we have shown that oxytocin administered to mothers can reach offspring brains with long lasting impacts on the development of social behaviors. Here, we examine the epigenetic and transcriptomic consequences of oxytocin exposure during birth in juvenile male offspring. more...

Organism:: Microtus ochrogaster

Type:: Expression profiling by high throughput sequencing

Platform:: GPL31149
6 Samples

Download data: CSV

Series

Accession:: GSE240832

ID:: 200240832

PubMed Similar studies

Select item 2002147982.

Transcription and DNA methylation signatures of paternal care in hippocampal dentate gyrus of prairie voles (RRBS)

(Submitter supplied) In socially monogamous prairie voles (Microtus ochrogaster), parental behaviors not only occur in mothers and fathers, but also can exist in virgin males. However, some virgin males display aggressive behaviors towards conspecific pups. Although this behavioral dichotomy in response to pup exposure has been well documented in male virgin voles, little is known about the gene expression changes underlie the parental behavioral differences and their regulatory mechanisms. more...

Organism:: Microtus ochrogaster

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL28499
23 Samples

Download data: TXT

Series

Accession:: GSE214798

ID:: 200214798

PubMed Full text in PMC Similar studies

Select item 2002147973.

Transcription and DNA methylation signatures of paternal care in hippocampal dentate gyrus of prairie voles (RNA-Seq)

(Submitter supplied) In socially monogamous prairie voles (Microtus ochrogaster), parental behaviors not only occur in mothers and fathers, but also can exist in virgin males. However, some virgin males display aggressive behaviors towards conspecific pups. Although this behavioral dichotomy in response to pup exposure has been well documented in male virgin voles, little is known about the gene expression changes underlie the parental behavioral differences and their regulatory mechanisms. more...

Organism:: Microtus ochrogaster

Type:: Expression profiling by high throughput sequencing

Platform:: GPL28499
23 Samples

Download data: TXT

Series

Accession:: GSE214797

ID:: 200214797

PubMed Full text in PMC Similar studies

Select item 2001500804.

Transcriptomic regulations underlying pair-bond formation and maintenance in the socially monogamous male and female prairie vole

(Submitter supplied) Background: The ability to form enduring social bonds is characteristic of human nature and as a result, impairments in social affiliation are central features of severe neuropsychiatric disorders including autism spectrum disorders and schizophrenia. Due to its ability to form long-term pair-bonds, the socially monogamous prairie vole (Microtus ochrogaster) has emerged as an excellent model to study the neurobiology of social attachment. more...

Organism:: Microtus ochrogaster

Type:: Expression profiling by high throughput sequencing

Platform:: GPL28499
46 Samples

Download data: TXT

Series

Accession:: GSE150080

ID:: 200150080

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001926615.

Adult male prairie vole nucleus accumbens RNAseq dataset for "Prolonged partner separation erodes nucleus accumbens transcriptional signatures of pair bonding in male prairie voles."

(Submitter supplied) This dataset contains RNA sequencing results from adult male prairie voles that were in either opposite-sex or same-sex pairs that were subsequently either separated from or remained paired with their partner for either 48 hours or 4 weeks prior to collecting nucleus accumbens tissue. The goal of this experiment was to determine the nucleus accumbens transcriptional response specific to separation from an opposite-sex partner. more...

Organism:: Microtus ochrogaster

Type:: Expression profiling by high throughput sequencing

Platform:: GPL31149
69 Samples

Download data: TXT

Series

Accession:: GSE192661

ID:: 200192661

PubMed Full text in PMC Similar studies

Select item 2001902136.

Transcriptomic analysis of paternal behaviors in prairie voles

(Submitter supplied) The importance of fathers' engagement in care and its critical role in the offspring’s cognitive and emotional development is now well established. Yet, little is known on the underlying neurobiology due to the lack of appropriate animal models. In the socially monogamous and bi-parental prairie vole (Microtus ochrogaster), while most virgin males show spontaneous paternal behaviors (Paternal), others display pup-directed aggression (Attackers). more...

Organism:: Microtus ochrogaster

Type:: Expression profiling by high throughput sequencing

Platform:: GPL28499
69 Samples

Download data: TXT

Series

Accession:: GSE190213

ID:: 200190213

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001233017.

Conserved Transcriptomic Profiles Underpin Monogamy across Vertebrates

(Submitter supplied) We compare fore- and mid-brain transcriptomes of reproductive males in monogamous and non-monogamous species pairs of Peromyscus mice, Microtus voles, parid songbirds, dendrobatid frogs, and Xenotilapia species of cichlid fishes. Our study provides evidence of a universal transcriptomic mechanism underlying the evolution of monogamy in vertebrates.

Organism:: Microtus pennsylvanicus; Peromyscus californicus; Xenotilapia spiloptera; Anthus spinoletta; Microtus ochrogaster; Peromyscus maniculatus; Ranitomeya imitator; Oophaga pumilio; Xenotilapia ornatipinnis; Prunella modularis

Type:: Expression profiling by high throughput sequencing

10 related Platforms
10 Samples

Download data: CSV, FASTA

Series

Accession:: GSE123301

ID:: 200123301

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000858268.

Becoming monogamous quickly: Adaptive evolution of a pallidal enhancer at the prairie vole Avpr1a locus

(Submitter supplied) We use ChIP-seq targeting histone 3 lysine 27-acetylation (H3K27ac) to identify putative enhancer sites genome-wide in the ventral pallidum cortex of adult prairie voles

Organism:: Microtus ochrogaster

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL22347
2 Samples

Download data: BEDGRAPH, TXT

Series

Accession:: GSE85826

ID:: 200085826

SRA Run Selector

Select item 2000736709.

Genome wide identification of enhancer regions in the retrosplenial cortex of the prairie vole, Microtus ochrogaster.

(Submitter supplied) We use ChIP-seq targeting histone 3 lysine 4 mono-methylation (H3K4me1) to identify putative enhancer sites genome-wide, in the retrosplenial cortex of adult prairie vole males.

Organism:: Microtus ochrogaster

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL20981
2 Samples

Download data: XLS

Series

Accession:: GSE73670

ID:: 200073670

PubMed Similar studies SRA Run Selector

Select item 30771025110.

Organism:: Microtus ochrogaster

Source name:: nucleus accumbens

Platform:: GPL31149
Series:: GSE240832 GSE240856

Sample

Accession:: GSM7710251

ID:: 307710251

SRA Run Selector

Select item 30771025011.

Organism:: Microtus ochrogaster

Source name:: nucleus accumbens

Platform:: GPL31149
Series:: GSE240832 GSE240856

Sample

Accession:: GSM7710250

ID:: 307710250

SRA Run Selector

Select item 30771024912.

Organism:: Microtus ochrogaster

Source name:: nucleus accumbens

Platform:: GPL31149
Series:: GSE240832 GSE240856

Sample

Accession:: GSM7710249

ID:: 307710249

SRA Run Selector

Select item 30771024813.

Organism:: Microtus ochrogaster

Source name:: nucleus accumbens

Platform:: GPL31149
Series:: GSE240832 GSE240856

Sample

Accession:: GSM7710248

ID:: 307710248

SRA Run Selector

Select item 30771024714.

Organism:: Microtus ochrogaster

Source name:: nucleus accumbens

Platform:: GPL31149
Series:: GSE240832 GSE240856

Sample

Accession:: GSM7710247

ID:: 307710247

SRA Run Selector

Select item 30771024615.

Organism:: Microtus ochrogaster

Source name:: nucleus accumbens

Platform:: GPL31149
Series:: GSE240832 GSE240856

Sample

Accession:: GSM7710246

ID:: 307710246

SRA Run Selector

Select item 30661609616.

RRBS Dentate Gyrus cells, Mother Group, Rep 6

Organism:: Microtus ochrogaster

Source name:: Dentate Gyrus

Platform:: GPL28499
Series:: GSE214798 GSE214799

Download data: TXT

Sample

Accession:: GSM6616096

ID:: 306616096

SRA Run Selector

Select item 30661609517.

RRBS Dentate Gyrus cells, Mother Group, Rep 5

Organism:: Microtus ochrogaster

Source name:: Dentate Gyrus

Platform:: GPL28499
Series:: GSE214798 GSE214799

Download data: TXT

Sample

Accession:: GSM6616095

ID:: 306616095

SRA Run Selector

Select item 30661609418.

RRBS Dentate Gyrus cells, Mother Group, Rep 4

Organism:: Microtus ochrogaster

Source name:: Dentate Gyrus

Platform:: GPL28499
Series:: GSE214798 GSE214799

Download data: TXT

Sample

Accession:: GSM6616094

ID:: 306616094

SRA Run Selector

Select item 30661609319.

RRBS Dentate Gyrus cells, Mother Group, Rep 3

Organism:: Microtus ochrogaster

Source name:: Dentate Gyrus

Platform:: GPL28499
Series:: GSE214798 GSE214799

Download data: TXT

Sample

Accession:: GSM6616093

ID:: 306616093

SRA Run Selector

Select item 30661609220.

RRBS Dentate Gyrus cells, Mother Group, Rep 2

Organism:: Microtus ochrogaster

Source name:: Dentate Gyrus

Platform:: GPL28499
Series:: GSE214798 GSE214799

Download data: TXT

Sample

Accession:: GSM6616092

ID:: 306616092

SRA Run Selector

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(txid79684[Organism:noexp]) AND gds_sra[filter] (250)
GEO DataSets
PMC Links for Nucleotide (Select 1677537993) (5)
PMC
NELL1 neural EGFL like 1 [Homo sapiens]
NELL1 neural EGFL like 1 [Homo sapiens]
Gene ID:4745

Gene
Gene Links for GEO Profiles (Select 113920836) (1)
Gene
Bangiaceae ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit (rbcL) ...
Bangiaceae ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit (rbcL) gene, partial cds; chloroplast.
PopSet: 941600967

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